The shield of micro-protector proteins in the human immune-verse against pathogens

A digital illustration of two hands cupping a yellow molecular structure and a blue DNA-like ring. The scene is surrounded by various colorful, stylized bacteria and viruses set against a cosmic background featuring a galaxy and a sunset over water.
Label
The shield of micro-protector proteins in the human immune-verse against pathogens
Artist
Krittika Roy
Description
GBPs (guanylate binding proteins, colored in yellow) act as one of the key effectors of the human immune system when there is bacterial, viral or protozoan attack. GBPs are known to localize to cellular membranes and have a variety of antimicrobial actions, including disrupting pathogen-containing vacuoles, limiting pathogen multiplication, increasing pathogen degradation, and causing apoptosis in infected cells. In addition, they have diverse functional significance in various cellular processes besides immunity, such as cell proliferation, motility, and vesicle trafficking. They also play vital roles in inflammatory reactions and several autoimmune disorders.
Type
Adobe Illustrator, Alphafold
Artist Affiliation
Graduate Student
Department
Institute of Molecular Biophysics
Area of Research
Structural biology and host-pathogen interactions
Research Group Site
Dr. Qian Yin
Date
2024